Clio is a newly funded autonomous vehicle in the conceptual design phase. Clio is intended to be a sampling platform that can be used simultaneously and independently of traditional wire based sampling systems. The goal of Clio is to lower operational and financial barriers to realizing a GENOTRACES “-omics” global survey of marine genomics (DNA), transcriptomics (RNA), proteomics (proteins and enzymes), metabolomics (lipids and other metabolites), and metallomics (metals).